Study Comparing Tarlatamab With Standard of Care Chemotherapy in Relapsed Small Cell Lung Cancer
- Trial number:
- NCT05740566
- Trial phase:
- 3
- Study type:
- Chemotherapy
- Overall status:
- Recruiting
Study start date
May, 2023
Scientific title
A Randomized, Open-label, Phase 3 Study of Tarlatamab Compared With Standard of Care in Subjects With Relapsed Small Cell Lung Cancer After Platinum-based First-line Chemotherapy
Summary
The main objective is to compare the efficacy of tarlatamab with standard of care (SOC) on prolonging overall survival (OS).
Participant has provided informed consent prior to initiation of any study specific activities/procedures.Age ≥ 18 years (or legal adult age within country, whichever is older) at the time of signing the informed consent. Histologically or cytologically confirmed SCLC with demonstrated progression or relapse. Participants who progressed or recurred following 1 platinum-based regimen. Measurable disease as defined per RECIST 1.1 within the 21-day screening period. Eastern Cooperative Oncology Group (ECOG) PS of 0 or 1. Minimum life expectancy of 12 weeks. Adequate organ function.
Study design
Primary purpose:
Treatment, Allocation:
Randomized, Intervention model:
Parallel Assignment, Masking:
None (Open Label),
Conditions
Small Cell Lung Cancer (SCLC)
Other study ID numbers
20210004
Choose trial site (220)
Tan Tock Seng Hospital Singapore
Baptist Cancer Center
Memphis, TN 38120, USA
National Hospital Organization Shikoku Cancer Center
甲１６０ Minamiumemotomachi, Matsuyama, Ehime 791-0245, Japan
Kindai University Hospital
377-2 Ōnohigashi, Osakasayama, Osaka 589-8511, Japan
Chungbuk National University Hospital
776 1sunhwan-ro, Seowon-gu, Cheongju-si, Chungcheongbuk-do, South Korea
National Cancer Center
323 Ilsan-ro, Goyang-si, Gyeonggi-do, South Korea
Gachon University Gil Hospital
783 Namdong-daero, Guwol-dong, Namdong-gu, Incheon, South Korea
Gyeongsang National University Hospital
79 Gangnam-ro, Jinju-si, Gyeongsangnam-do, South Korea
Severance Hospital Yonsei University Health System
50-1 Yonsei-ro, Sinchon-dong, Seodaemun-gu, Seoul, South Korea
Asan Medical Center
88 Olympic-ro 43-gil, Songpa-gu, Seoul, South Korea
Samsung Medical Center
81 Irwon-ro, Gangnam-gu, Seoul, South Korea
Ulsan University Hospital
South Korea, Ulsan, Dong-gu, 대학병원로 25
Memorial Ankara Hastanesi
Balgat Mah. Mevlana Bulv, Balgat, 1422. Sk. No: 4, 06520 Çankaya/Ankara, Türkiye
Ankara Bilkent Sehir Hastanesi
Üniversiteler, 1604. Cd. No:9, 06800 Çankaya/Ankara, Türkiye
Pamukkale Universitesi Tip Fakultesi Hastanesi
Denizli, Kumkısık, Denizli, Türkiye
Medipol Mega Universite Hastanesi
TEM Avrupa otoyolu göztepe çıkışı no:1, Göztepe, 34214 Bağcılar/İstanbul, Türkiye
Goztepe Prof Dr Suleyman Yalcin Sehir Hastanesi
Eğitim, Göztepe Araştırma Hst., 34722 Kadıköy/İstanbul, Türkiye
Izmir Ekonomi Universitesi Medical Point Hastanesi
Yeni Girne Bulvarı, İmbatlı, 1825. Sk. No:12, 35575 Karşıyaka/İzmir, Türkiye
Inonu Universitesi Turgut Ozal Tip Merkezi
Bulgurlu Mahallesi, Bulgurlu, Elazığ Yolu 15. Km., 44280 Merkez/Battalgazi/Battalgazi/Malatya, Türkiye
University of Tennessee Medical Center Knoxville
1924 Alcoa Highway Suite Np 100, Knoxville, TN 37920, USA
Instituto Argentino de Diagnostico y Tratamiento IADT
Buenos Aires, Argentina
Calvary Mater Newcastle Hospital
20 Edith St, Waratah NSW 2298, Australia
Monash Medical Centre
246 Clayton Rd, Clayton VIC 3168, Australia
The Alfred Hospital
55 Commercial Rd, Melbourne VIC 3004, Australia
Okayama University Hospital
2-chōme-5-1 Shikatachō, Kita Ward, Okayama, 700-8558, Japan
Kansai Medical University Hospital
Japan, 〒573-1191 Osaka, Hirakata, Shinmachi, 2-chōme−３−１
Seoul National University Bundang Hospital
82 Gumi-ro 173beon-gil, Bundang-gu, Seongnam-si, Gyeonggi-do, South Korea
Kantonsspital Graubuenden
Loestrasse 170, 7000 Chur, Switzerland
Kantonsspital Sankt Gallen
St Gallen, Switzerland
Kantonsspital Winterthur
Winterthur, Switzerland
National Taiwan University Hospital
No. 7號, Zhongshan S Rd, Zhongzheng District, Taipei City, Taiwan 100
Taipei Veterans General Hospital
Taipei City, Taiwan
Cemic
Buenos Aires, Argentina
Hadassah Ein-Kerem Medical Center
Kalman Ya'akov Man St, Jerusalem, Israel
National Cancer Center Hospital East
Japan, 〒277-8577 Chiba, Kashiwa, Kashiwanoha, 6-chōme−５−１
National Hospital Organization Hokkaido Cancer Center
2-chōme-3-54 Kikusui 4 Jō, Shiroishi Ward, Sapporo, Hokkaido 003-0804, Japan
Hyogo Cancer Center
13-70 Kitaōjichō, 北王子町 Akashi, Hyogo 673-0021, Japan
Sendai Kousei Hospital
Japan, 〒980-0873 Miyagi, Sendai, Aoba Ward, Hirosemachi, 4−１５ 2階
Shizuoka Cancer Center
1007 Shimonagakubo, Nagaizumi, Sunto District, Shizuoka 411-8777, Japan
The Cancer Institute Hospital of Japanese Foundation for Cancer Research
3-chōme-8-31 Ariake, Koto City, Tokyo 135-0063, Japan
Kaohsiung Medical University Chung-Ho Memorial Hospital
No. 100號, Ziyou 1st Rd, Sanmin District, Kaohsiung City, Taiwan 80756
National Cheng Kung University Hospital
Tainan City, Taiwan
National Cancer Centre Singapore
Alaska Oncology and Hematology LLC
2925 DeBarr Rd Building D, Suite 300, Anchorage, AK 99508, USA
University of Arkansas for Medical Sciences
4301 W Markham St, Little Rock, AR 72205, USA
Indiana U Simon Cancer Center
535 Barnhill Dr, Indianapolis, IN 46202, USA
Pikeville Medical Center
Pikeville, KY 41501, USA
Our Lady of the Lake Cancer Institute
7777 Hennessy Blvd, Baton Rouge, LA 70808, USA
Trinity Health Saint Joseph Mercy Ann Arbor
Ann Arbor, MI 48106, USA
New York University Langone Health
New York, NY 10016, USA
Perlmutter Cancer Center at New York University Langone Hospital----Long Island
160 E 34th St, New York, NY 10016, USA
Memorial Sloan Kettering Cancer Center
530 E 74th St, New York, NY 10021, USA
Sanford Roger Maris Cancer Center
820 4th St N, Fargo, ND 58102, USA
Sanford Oncology Clinic and Pharmacy
Sioux Falls, SD 57104, USA
Swedish Cancer Institute Medical Oncology
21605 76th Ave W, Edmonds, WA 98026, USA
The Medical College of Wisconsin
Wauwatosa, WI 53226, USA
Hospital Universitario Austral
Pilar, Buenos Aires Province, Argentina
Clinica Viedma
Sarmiento 253, R8500 Viedma, Río Negro, Argentina
Sanatorio Parque SA
Blvd. Oroño 860, S2000 Rosario, Santa Fe, Argentina
Sanatorio Allende
Córdoba, Córdoba Province, Argentina
Liverpool Hospital
Burnside Dr, Liverpool NSW 2170, Australia
Jessa Ziekenhuis - Campus Virga Jesse
Stadsomvaart 11, 3500 Hasselt, Belgium
AZ Delta Campus Rumbeke
Deltalaan 1, 8800 Roeselare, Belgium
Vitaz campus Sint-Niklaas Moerland
Moerlandstraat 1, 9100 Sint-Niklaas, Belgium
Hospital Santa Izabel
Praça Conselheiro Almeida Couto, 500 - Nazaré, Salvador - BA, 40050-410, Brazil
Instituto de Ensino e Pesquisa do Hospital da Bahia
Av. Prof. Magalhães Neto, 1541 - Pituba, Salvador - BA, 41810-011, Brazil
Liga Norte-Riograndense Contra O Cancer
Av. Miguel Castro, 1355 - Nossa Sra. de Nazaré, Natal - RN, 59062-000, Brazil
Oncosite Centro de Pesquisa Clinica Em Oncologia Ltda
Ijuí, RS, 98700-000, Brazil
Hospital Sao Lucas da Pontificia Universidade Catolica do Rio Grande do Sul
Av. Ipiranga, 6681 - Partenon, Porto Alegre - RS, 90619-900, Brazil
Hospital de Amor Amazonia
15 - BR-364 - Porto Velho, RO, 76834-899, Brazil
Beneficencia Portuguesa de Sao Paulo
R. Maestro Cardim, 637 - Bela Vista, São Paulo - SP, 01323-001, Brazil
Oncologia Rede D Or
Vila Nova Conceição, São Paulo - State of São Paulo, 04506-000, Brazil
Hospital de Base de Sao Jose do Rio Preto
Av. Brg. Faria Lima, 5544 - Vila Sao Jose, São José do Rio Preto - SP, 15090-000, Brazil
Anhui Chest Hospital
R7V6+H2X, Fei Xi Lu, Shu Shan Qu, He Fei Shi, An Hui Sheng, China, 230039
Beijing Tongren Hospital affiliated to Capital Medical University
WFF2+WP8, Dong Da Qiao Xie Jie, 使馆区 Chao Yang Qu, Bei Jing Shi, China, 100020
Beijing Cancer Hospital
52 Fu Cheng Lu, Hai Dian Qu, Bei Jing Shi, China, 100142
The Second Affiliated Hospital of Army Military Medical University
China, Chong Qing Shi, Sha Ping Ba Qu, 高滩岩正街30号 邮政编码: 400037
Army Special Medical Center of People's Liberation Army
China, 400042
Fujian Medical University Union Hospital
2 Gu Tian Lu, Gu Lou Qu, Fu Zhou Shi, Fu Jian Sheng, China, 350004
Mengchao Hepatobiliary Hospital of Fujian Medical University
312 Xi Hong Lu, Gu Lou Qu, Fu Zhou Shi, Fu Jian Sheng, China, 350025
Sun Yat-Sen University Cancer Center
China, Guang Dong Sheng, Guang Zhou Shi, Yue Xiu Qu, 东风东路651号 邮政编码: 510060
Jiangmen Central Hospital
China, Guang Dong Sheng, Jiang Men Shi, Peng Jiang Qu, 北街海旁街23号 邮政编码: 529030
Affiliated Cancer Hospital of Harbin Medical University
157 Bao Jian Lu, Nan Gang Qu, Ha Er Bin Shi, Hei Long Jiang Sheng, China, 150088
Union Hospital Tongji Medical College Huazhong University of Science and Technology
China, Hu Bei Sheng, Wu Han Shi, Jiang An Qu, 三阳路 邮政编码: 430014
Tongji Hospital Tongji Medical College Huazhong University of Science and Technology
China, Hu Bei Sheng, Wu Han Shi, Jiang An Qu, 三阳路 邮政编码: 430014
The First Affiliated Hospital of Nanchang University
Nanchang, Jiangxi, China
Jinan Central Hospital
105 Jie Fang Lu, Li Xia Qu, Ji Nan Shi, Shan Dong Sheng, China, 250013
Shandong Tumor Hospital
M2PX+549, Huang Tai Nan Lu, Li Xia Qu, Ji Nan Shi, Shan Dong Sheng, China, 250199
Linyi Cancer Hospital
China, 6, Lan Shan Qu, 沂市肿瘤医院 CN 山东省 临沂市 邮政编码: 276001
Shanxi Province Cancer Hospital
Taiyuan, China, 030013
Zhejiang Cancer Hospital
Hangzhou, China, 310005
Taizhou Peoples Hospital
Taizhou, Zhejiang, China
The First Affiliated Hospital of Wenzhou Medical University
Ouhai District, Wenzhou, China, 325015
Beijing Chest Hospital, Capital Medical University
China, Bei Jing Shi, Tong Zhou Qu, Tong Shun Lu, 北马厂97号 邮政编码: 101125
Weihai Municipal Hospital
China, Shan Dong Sheng, Wei Hai Shi, Huan Cui Qu, 和平路70号 邮政编码: 264299
Masarykuv onkologicky ustav
Žlutý kopec 543/7, 602 00 Brno-střed-Staré Brno, Czechia
Nemocnice Agel Ostrava-Vitkovice as
15, Zalužanského 1192, 703 00 Ostrava-Vítkovice, Czechia
Rigshospitalet
Blegdamsvej 9, 2100 København, Denmark
Centre Hospitalier Lyon Sud
165 Chem. du Grand Revoyet, 69495 Oullins-Pierre-Bénite, France
Universitaetsklinikum Carl Gustav Carus
Fetscherstraße 74, 01307 Dresden, Germany
Universitaetsklinikum Essen
Hufelandstraße 55, 45147 Essen, Germany
Universitaetsklinikum Wuerzburg
Josef-Schneider-Straße 2, 97080 Würzburg, Germany
Saint Savas Hospital
Dimitsanas 26, Μενεμένη 115 22, Greece
Henry Dunant Hospital Center
Leof. Mesogeion 107, Athina 115 26, Greece
Alexandra Hospital
Lourou 4-2, Athina 115 28, Greece
University Hospital of Heraklion
Leof. Panepistimiou, Iraklio 715 00, Greece
Olympion Therapeftirio General Clinic Of Patras
Olympion, Patra 264 43, Greece
Saint Luke Hospital
SAINT LUKE, Panorama 552 36, Greece
European Interbalkan Medical Center
Asklipiou 10, Pilea 555 35, Greece
Matrai Gyogyintezet
Gyöngyös, 3200 Hungary
Komarom-Esztergom Varmegyei Szent Borbala Korhaz
Tatabánya, Dózsa György út 77, 2800 Hungary
Torokbalinti Tudogyogyintezet
Törökbálint, Munkácsy Mihály u. 70, 2045 Hungary
Rambam Medical Center
HaAliya HaShniya St 8, Haifa, 3109601, Israel
Rabin Medical Center
Zeev Jabotinsky St 39, Petah Tikva, 4941492, Israel
Humanitas Gavazzeni
Via Mauro Gavazzeni, 21, 24125 Bergamo BG, Italy
National Hospital Organization Nagoya Medical Center
4-chōme-1-1 Sannomaru, Naka Ward, Nagoya, Aichi 460-0001, Japan
Aichi Cancer Center
1-1 Kanokoden, Chikusa Ward, Nagoya, Aichi 464-8681, Japan
Kurume University Hospital
67 Asahimachi, Kurume, Fukuoka 830-0011, Japan
Kanagawa Prefectural Hospital Organization Kanagawa Cancer Center
2-chōme-3-2 Nakao, Asahi Ward, Yokohama, Kanagawa 241-8515, Japan
Niigata Cancer Center Hospital
2-chōme-15-3 Kawagishichō, Chuo Ward, Niigata, 951-8133, Japan
Osaka International Cancer Institute
3-chōme-1-69 Ōtemae, Chuo Ward, Osaka, 540-0008, Japan
Saitama Medical University International Medical Center
1397-1 Yamane, Hidaka, Saitama 350-1298, Japan
National Cancer Center Hospital
5-chōme-1-1 Tsukiji, Chuo City, Tokyo 104-0045, Japan
Wakayama Medical University Hospital
811番地１ Kimiidera, Wakayama, 641-0012, Japan
Chungbuk National University Hospital
776 1sunhwan-ro, Seowon-gu, Cheongju, Chungcheongbuk-do, South Korea
The Catholic University of Korea Seoul St Marys Hospital
222 Banpo-daero, Seocho-gu, Seoul, South Korea
Hospital Tengku Ampuan Afzan
Jalan Tanah Putih, 25100 Kuantan, Pahang, Malaysia
Sarawak General Hospital
Jalan Hospital, 93586 Kuching, Sarawak, Malaysia
University Malaya Medical Centre
Jln Profesor Diraja Ungku Aziz, Seksyen 13, 50603 Petaling Jaya, Selangor, Malaysia
Szpital Specjalistyczny imienia Ludwika Rydygiera w Krakowie Sp zoo
Osiedle Złotej Jesieni 1, 31-826 Kraków, Poland
Wielkopolskie Centrum Pulmonologii i Torakochirurgii imienia Eugenii i Janusza Zeylandow
Szamarzewskiego 62, 60-569 Poznań, Poland
Hospital da Luz, SA
Av. Lusíada 100, 1500-650 Lisboa, Portugal
Institutul Oncologic Prof Dr Ion Chiricuta Cluj-Napoca
Cluj-Napoca, Romania
Centrul de Oncologie Sf Nectarie SRL
Strada Caracal 109, Craiova, Romania
SC Oncomed SRL
Timișoara, Romania
National Cancer Centre Singapore
30 Hospital Blvd, Singapore 168583
Tan Tock Seng Hospital
11 Jln Tan Tock Seng, Singapore 308433
Hopitaux universitaires de Geneve
1211 Geneva, Switzerland
Veterans General Hospital - Taichung
Central District, Taichung City, Taiwan 400
Ege Universitesi Tip Fakultesi Hastanesi
Kazımdirik, Üniversite Cd. No:9, 35100 Bornova/İzmir, Türkiye
University of Illinois at Chicago
1200 W Harrison St, Chicago, IL 60607, USA
University of Missouri Health Care
1 Hospital Dr, Columbia, MO 65212, USA
Medizinische Universitaet Graz
Neue Stiftingtalstraße 6, 8010 Graz, Austria
Universitaetsklinikum Krems
Mitterweg 10, 3500 Krems an der Donau, Austria
Universitair Ziekenhuis Gent
Corneel Heymanslaan 10, 9000 Gent, Belgium
Hospital de Amor da Amazonia
15 - BR-364 - Porto Velho, RO, 76834-899, Brazil
Instituto Coi
Av. das Américas, 6205 - loja E - Barra da Tijuca, Rio de Janeiro - RJ, 22793-080, Brazil
Instituto do Cancer do Estado de Sao Paulo Octavio Frias de Oliveira Icesp
Av. Dr. Arnaldo, 251 - Cerqueira César, São Paulo - SP, 01246-000, Brazil
Princess Margaret Cancer Centre
610 University Ave, Toronto, ON M5G 2C4, Canada
The Second Affiliated Hospital of Army Medical University, PLA
China, Chong Qing Shi, Sha Ping Ba Qu, 高滩岩正街30号 邮政编码: 400037
Army Special Medical Center of Peoples Liberation Army
China, 400042
Fudan University Shanghai Cancer Center
270 Dong An Lu, 270, Xu Hui Qu, Shang Hai Shi, China, 200032
The Second Affiliated Hospital Zhejiang University School of Medicine
88 Jie Fang Lu, Shang Cheng Qu, Hang Zhou Shi, Zhe Jiang Sheng, China, 310009
Tianjin Peoples Hospital
China, Tian Jin Shi, Hong Qiao Qu, 水西道44XW+HJM 邮政编码: 300122
Fakultni nemocnice Brno
Jihlavská 340/20, 625 00 Brno-Bohunice-Brno-Starý Lískovec, Czechia
Vseobecna fakultni nemocnice v Praze
Prague, Czechia
Centre Hospitalier Universitaire de Grenoble - Hopital Nord Michallon
Av. des Maquis du Grésivaudan, 38700 La Tronche, France
Centre Hospitalier Régional Universitaire de Lille - Institut Coeur Poumon
2 Av. Oscar Lambret, 59000 Lille, France
Centre Hospitalier Regional Universitaire de Limoges - Hopital Dupuytren
33 Rue François Mitterrand, 87000 Limoges, France
Centre Hospitalier Universitaire Nord
Marseille, France
Institut Curie
75005 Paris, France
Centre Hospitalier Universitaire de Rennes - Hopital Pontchaillou
2 Rue Henri le Guilloux, 35000 Rennes, France
Centre Hospitalier Universitaire de Toulouse - Hopital Larrey
2 Rue Charles Viguerie, 31300 Toulouse, France
LungenClinic Grosshansdorf GmbH
Wöhrendamm 80, 22927 Großhansdorf, Germany
Thoracic General Hospital Of Athens Sotiria
Mesogion 152, Athina 115 27, Greece
Semmelweis Egyetem
Budapest, 1083 Hungary
Orszagos Koranyi Pulmonologiai Intezet
Budapest, Korányi Frigyes út 1, 1122 Hungary
Istituto Romagnolo per lo Studio dei Tumori Dino Amadori
Via Piero Maroncelli, 40, 47014 Meldola FC, Italy
Azienda Ospedaliera Universitaria San Luigi Gonzaga
Regione Gonzole, 10, 10043 Orbassano TO, Italy
Azienda Ospedaliera San Giovanni Addolorata
Azienda Ospedaliera S. Giovanni Addolorata, 00184 Roma RM, Italy
Juntendo University Hospital
3-chōme-1-3 Hongō, Bunkyo City, Tokyo 113-0033, Japan
Universitair Medisch Centrum Groningen
Hanzeplein 1, 9713 GZ Groningen, Netherlands
Erasmus Medisch Centrum
Dr. Molewaterplein 40, 3015 GD Rotterdam, Netherlands
Universitair Medisch Centrum Utrecht
Heidelberglaan 100, 3584 CX Utrecht, Netherlands
Centrum Pulmonologii i Torakochirurgii w Bystrej
Juliana Fałata 2, 43-360 Bystra, Poland
Hospital Cuf Descobertas
Lisbon, Portugal
Unidade Local de Saude de Matosinhos, EPE - Hospital Pedro Hispano
R. de Dr. Eduardo Torres, 4460 Sra. da Hora, Portugal
Hospital Cuf porto
Estr. da Circunvalação 14341, 4100-180 Porto, Portugal
Institutul Regional de Oncologie Iasi
Iași, Romania
Hospital Regional Universitario de Malaga
Av. de Carlos Haya, 84, Bailén-Miraflores, 29010 Málaga, Spain
Hospital del Mar
Pg. Marítim de la Barceloneta, 25, 29, Ciutat Vella, 08003 Barcelona, Spain
Hospital de la Santa Creu i Sant Pau
C/ de Sant Quintí, 89, Horta-Guinardó, 08025 Barcelona, Spain
Complexo Hospitalario Universitario A Coruña Hospital Teresa Herrera
Xubias de Abaixo, s/n, 15009 A Coruña, Spain
Hospital Universitario Puerta de Hierro Majadahonda
C. Joaquín Rodrigo, 1, 28222 Majadahonda, Madrid, Spain
Fundacion Jimenez Diaz
Av. de los Reyes Católicos, 2, Moncloa - Aravaca, 28040 Madrid, Spain
Hospital Clinico San Carlos
Calle del Prof Martín Lagos, S/N, Moncloa - Aravaca, 28040 Madrid, Spain
Hospital Universitario 12 de Octubre
Universidad Privada Camilo José Cela, Villaverde, 28041 Madrid, Spain
Freiburg Spital
Fribourg, Switzerland
Alaska Oncology and Hematology
2925 Debarr Road Building D, Suite 300, Anchorage, AK 99508, USA
University of Iowa
Iowa City, IA 52242, USA
Summit Medical Group, Overlook Oncology Center
Overlook Rd, Summit, NJ 07901, USA
Subei Peoples Hospital
Nan Tong Xi Lu, Guangling Qu, Yangzhou Shi, Jiangsu Sheng, China
Fakultni nemocnice Olomouc
6, I.P. Pavlova 185, Nová Ulice, 779 00 Olomouc, Czechia
Centre Leon Berard
28 Prom. Léa et Napoléon Bullukian, 69008 Lyon, France
Centre Hospitalier Universitaire de Strasbourg - Nouvel Hopital Civil
1 Pl. de l'Hôpital, 67000 Strasbourg, France
Charite Universitaetsmedizin Berlin, Campus Virchow
Eingang A, Mittelallee 10/1.2853, 13353 Berlin, Germany
Universitaetsklinikum Dresden
Fetscherstraße 74, 01307 Dresden, Germany
Asklepios Fachkliniken Muenchen Gauting
82131 Gauting, Germany
Universitaetsklinikum Koeln
Kerpener Str. 62, 50937 Köln, Germany
Robert-Bosch-Krankenhaus
Auerbachstraße 110, 70376 Stuttgart, Germany
Meir Medical Center
Tchernichovsky St 59, Kefar Sava, 4428164, Israel
Azienda Ospedaliera Universitaria Renato Dulbecco
Via Martiri di Cefalonia, 2E, 88100 Catanzaro CZ, Italy
Ospedale Policlinico San Martino IRCCS
Largo Rosanna Benzi, 10, 16132 Genova GE, Italy
Leids Universitair Medisch Centrum
Albinusdreef 2, 2333 ZA Leiden, Netherlands
Hospital Clinico Universitario Lozano Blesa
C. de San Juan Bosco, 15, 50009 Zaragoza, Spain
Hospital Universitari Vall d Hebron
Passeig de la Vall d'Hebron, 119, 08035 Barcelona, Spain
Gazi Universitesi Saglik Arastirma ve Uygulama Merkezi Gazi Hastanesi
Emniyet, Bahriye Üçok Cd., 06560 Yenimahalle/Ankara, Turkey