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Found:
10 trials shown from 1139 total

Biomarkers in Samples From Patients With Endometrial Cancer

This research study is studying biomarkers in samples from patients with endometrial cancer. Studying samples from patients with cancer in the laboratory may help doctors learn mor

Study number:
NCT01199250
Cohorts:
1
Study phase:
N/A
Overall status:
Not yet recruiting
Study type:
Observational, Biomarker

Novartis

Key trial

Dose Optimization and Expansion Study of DFV890 in Adult Patients With Myeloid Diseases

Study CDFV890G12101 is an open-label, phase 1b, multicenter study with a randomized two-dose optimization part, and a dose expansion part consisting of two groups evaluating DFV890

Study number:
NCT05552469
Cohorts:
1
Study phase:
1
Overall status:
Not yet recruiting
Study type:
Targeted therapy

A Study Evaluating the Efficacy and Safety of Inavolisib Plus Fulvestrant Compared With Alpelisib Plus Fulvestrant in Participants With HR-Positive, HER2-Negative, PIK3CA Mutated, Locally Advanced or Metastatic Breast Cancer Post CDK4/6i and Endocrine Combination Therapy

This is a Phase III, multicenter, randomized, open-label, global study designed to evaluate the efficacy and safety of inavolisib plus fulvestrant compared with alpelisib plus fulv

Study number:
NCT05646862
Cohorts:
1
Study phase:
3
Overall status:
Not yet recruiting
Study type:
Targeted therapy, Hormonal therapy

Phase II Lenvatinib and Pembrolizumab in Endocrine Resistant Breast Cancer With Letrozole

This is a phase II study testing the combination of pembrolizumab with lenvatinib, a multi-kinase inhibitor that has activity against vascular endothelial growth factor receptors 1

Study number:
NCT05286437
Cohorts:
1
Study phase:
2
Overall status:
Recruiting
Study type:
Targeted therapy, Hormonal therapy

19F Hot Spot MRI of Human Adipose-derived Stem Cells for Breast Reconstruction

Six female patients (>18 years of age, pre-menopausal) who have had loco-regional (lumpectomy and radiation) therapy for breast carcinoma and have been at least one-year disease fr

Study number:
NCT02035085
Cohorts:
1
Study phase:
1
Overall status:
Recruiting
Study type:
Supportive interventions, Local/Regional therapies, Observational

A Novel Limb Cryocompression System for Prevention of Chemotherapy Induced Peripheral Neuropathy - Expansion Study

The study conducted on cancer patients is designed to test safety and efficacy of limb hypothermia in cancer patients using the new Paxman Limb Cryocompression System (PLCS). Ultim

Study number:
NCT05606068
Cohorts:
1
Study phase:
N/A
Overall status:
Not yet recruiting
Study type:
Chemotherapy, Supportive interventions

A Study Evaluating the Efficacy and Safety of Multiple Therapies in Cohorts of Participants With Locally Advanced, Unresectable, Stage III Non-Small Cell Lung Cancer (NSCLC)

This study will evaluate the efficacy and safety of multiple therapies in participants with locally advanced, unresectable, Stage III NSCLC with eligible biomarker status as determ

Study number:
NCT05170204
Cohorts:
1
Study phase:
3
Overall status:
Recruiting
Study type:
Targeted therapy

A Study of SCG101 in the Treatment of Subjects With Hepatitis B Virus-Related Hepatocellular Carcinoma

This Phase 1/ 2 study is a multicenter study to evaluate the safety, tolerability and efficacy of SCG101 in subjects with hepatitis B virus-related hepatocellular carcinoma

Study number:
NCT05417932
Cohorts:
1
Study phase:
1, 2
Overall status:
Recruiting
Study type:
Immunotherapy

Novartis

Key trial

Platform Study of JDQ443 in Combinations in Patients With Advanced Solid Tumors Harboring the KRAS G12C Mutation

This is Phase Ib/II, multicenter, open-label adaptive platform study of JDQ443 with select therapies in patients with advanced solid tumors harboring the KRAS G12C mutation.

Study number:
NCT05358249
Cohorts:
1
Study phase:
1, 2
Overall status:
Recruiting
Study type:
Targeted therapy, Biomarker

Zimberelimab and Domvanalimab in Combination With Chemotherapy Versus Pembrolizumab With Chemotherapy in Patients With Untreated Metastatic Non-Small Cell Lung Cancer

The primary objective of this study is to compare the effect of zimberelimab (ZIM) and domvanalimab (DOM) in combination with chemotherapy relative to pembrolizumab (PEMBRO) in com

Study number:
NCT05502237
Cohorts:
1
Study phase:
3
Overall status:
Recruiting
Study type:
Immunotherapy, Targeted therapy